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Description

The cellular response to external factors amplifies the initial biochemical reactions, building up effects on metabolite networks within time intervals ranging from seconds to hours

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Jones RN, Rando RJ, Glindmeyer HW, Foster TA, Hughes JM, O'Neil CE, & Weill H (1992) Abnormal lung function in polyurethane foam producers: Weak relationship to toluene diisocyanate exposures

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The mitochondria, peroxisomes, endoplasmic reticulum, endothelial cells, neutrophils, macrophages, xanthine oxidoreductase and myeloperoxidase are endogenous source of ROS generation [18,19,20]