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The duration of use of each agent is unclear, with most studies evaluating the treatment of CIPN over periods ranging from 2 weeks to as much as 12 weeks

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With certain genetic inefficiencies, glutathione production can be reduced 50% or more, and it is estimated that nearly 1 in 3 people has this genetic variant

Oct 19;12(11):11000-12

Wilk AJ, Rustagi A, Zhao NQ, Roque J, Martnez-Coln GJ, McKechnie JL, et al

By contrast, APEX2, also targeted to the cell surface, provided much weaker staining of the plasma membrane relative to intracellular organelles (Supplementary Fig