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Engel 4 , (1)Ucm Digestive Diseases, Virgen Del Rocio University Hospital, Instituto De Biomedicina De Sevilla, Ciberehd, University of Seville, Sevilla, Spain, (2)Texas Liver Institute, University of Texas Health San Antonio, San Antonio, TX, USA, (3)Merck & Co., Inc., Rahway, NJ, USA, (4)Global Clinical Development, Merck & Co., Inc., Rahway, NJ, USA Background: Hispanic (HISP) patients have been reported to have a higher prevalence and severity of nonalcoholic steatohepatitis (NASH) compared to other ethnicities in the USA

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Results: Here, we revealed that NEN mediates AMPK-mediated phosphorylation of p62 at Ser351, resulting in activation of noncanonical Nrf2 pathway

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Actionable Lifestyle Strategies to Maximize Metabolic Shifting Research compounds should never be viewed as magic bullets that operate in a vacuum

Redox proteomics analysis in AD brain also led to the identification of increased oxidation of non-energetic-related proteins in the mitochondria, such as the superoxide radical scavenger MnSOD and voltage-dependent anion channels (VDACs) (27, 306, 310)