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Recent research has identified the signaling pathway JAK-STAT as particularly involved, which has led to the development of JAK inhibitors (first specific treatment approved in 2022)

Controls were treated with 1 PBS and showed 100% growth, while tests measured the percentage decrease in biofilm biomass with respect to this control

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Conclusion: In our prospective study, the GALAD score performed better for HCC surveillance in our population compared to the GAAD score as it is better able to portend the development of HCC within a year using the manufacturers recommended cut-off value