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Metabolic dependencies and targets in ovarian cancer

41 BudenzD.AndersonD.VarmaR.SchumanJ.CantorL.SavellJ.et al (2007)

AAV1/2-Induced Overexpression of A53T--Synuclein in the Substantia Nigra Results in Degeneration of the Nigrostriatal System With Lewy-Like Pathology and Motor Impairment: A New Mouse Model for Parkinsons Disease

Mice with inactive IGF-IR in orexin neurons (Firoc mice) express a truncated IGF-IR in the hypothalamus, as determined by PCR detection of the truncated IGF-IR (Figure 1A)