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Thus, the promotion of biogenesis via the SIRT1/PGC-1 signaling pathway could be a target for new therapies to prevent mitochondrial dysfunctions in neuronal injuries [89]

Summary Keywords autism spectrum disorder, gut-brain axis, gut microbiota, dietary intervention strategies, microbiota-metabolism axis Citation Fang Z, Zhou Y, Chen K, Wang J, Liu X and Jia P (2025) Gut microbiota and autism spectrum disorder: advances in dietary intervention strategies based on the microbiota-gut-brain axis mechanism

But heres the comparison that should reframe your priorities: loneliness has the equivalent health effect of smoking 15 cigarettes a day

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Ferrere et al