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In addition, there is a higher intensity of CD38 expression (measured by flow cytometry) in the more aggressive multi-hit variants, which allows further differentiation of the diseases and the use of CD38 as a biomarker for early diagnosis [14]

Peptide degradation during improper storage shortens the active fraction available at the time of administration

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Require diagnosis and monitoring: Some conditions (like high blood pressure, diabetes, or bacterial infections) need a professional diagnosis and ongoing monitoring