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Ischemia-reperfusion injury suppresses the expression of tau protein, triggers iron accumulation in neurons, and promotes ferroptosis ( 3.5.2 Hemorrhagic stroke Research has investigated that ferroptosis occurs in experimental cerebral hemorrhage (CH) models and brain tissues of patients affected by CH (Zille et al., 2017

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The systemic sub-inflammatory state of PD is induced by the relative abundances of Verrucomicrobia and Bacteroides which are linked to higher plasma levels of TNF- and IFN- (86) (Figure 2)