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As the hippocampus and adult hippocampal neurogenesis (AHN)a neuronal maturation process dependent on NSCsare important for learning, cognition, and memory, disrupted hippocampal function and suppressed neurogenesis contribute to the development of depression (Yirmiya and Goshen, 2011

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Nature cell biology

In brief, 20 l of Viability/Cytotoxicity Reagent containing both GF-AFC was added to each well, followed by 30 sec mixing at room temperature and incubation at 37C for 30 min

Researchers study it to understand how this endogenous complex influences tissue repair, antioxidant defense, and cellular communication in experimental settings, particularly focusing on why its natural decline correlates with aging changes

So far, these monitors have prevented over 2,500 blockages in targeted areas