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doi: 10.1016/j.stem.2019.12.015

Their structural diversity and biocompatibility make them important resources for drug discovery, capable of interfering with the immune-metabolic network of PH through multiple pathways (Zhang et al., 2021

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10.1074/jbc.M808515200 J

Reported tolerability in the available human observational work is high: no consistent pattern of adverse effects has been published, although the absence of placebo-controlled trials means subtle effects cannot be excluded