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Certain groups should avoid this medication or use it with caution: Pregnant and breastfeeding women: Doxycycline can affect the development of the fetus, particularly the teeth and bones, so it's usually not recommended during pregnancy

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It is also heavily involved in immune system function and muscle protein synthesis

Moreover, quercetin induces relevant genetic expression and production of T helper (Th) Th-1-derived interferon (IFN)- and inhibits enzymes such as lipoxygenase and cyclooxygenase, reducing the production of molecules like thromboxane, prostaglandins, and leukotrienes involved in type 2 reactions [44]

PMID: 40557718 bioRxiv 2024 Oct 13:2024.10.10.617667

Another study using primary cortical neurons cultured from Pink1 -deficient mice revealed that FKBP5 can reduce Akt phosphorylation and promote MPP + -mediated neuronal death in the absence of Pink1 [91]