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J Biol Chem 292:26602669

In this study, we observed hepatomegaly with visible necrotic foci on the hepatic surface in HE rat models

Its just a theory, and its been used as a theory, but its turned into dogma

The previously mentioned study on rats with open ischemic wounds also reported an apparent decrease in wound area of the GHK-Cu group that was greater compared to the control group on days 3 to 5, 6 to 9, and 11 to 13