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The main difference between this and atrophic hypothyroidism, is that atrophic hypothyroidism does not cause goitre, but that Hashimotos can do

However, when taking into account the moderately elevated precursor IL-1 levels in Il1b K133R/K133R macrophages, the observed ubiquitylation pattern indicates a possible reduction in IL-1 K133R ubiquitylation, particularly its decoration with K11-linked ubiquitin chains (Fig

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