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In particular, excessive intake of Vitamin B6 can cause nerve damage, and too much Niacin may lead to liver damage

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While a small number of studies have shown some improvement in children with autism who were treated with leucovorin, many autism researchers and advocates argue the announcement is premature and more research is needed

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A common clinical observation has been that, as the child gains core strength and increased sensation in the oral-motor pathways, oral stims sometimes become more frequent (and alarm the parent that the child is regressing)

Thanks Hi bubblesmcgee a wiser person than I has posted this previously " The pimples/acne, is likely to be caused by microbes on your skin reacting to the additional B12 by producing substances that your skin is then reacting to