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2023 Nov:67:102905

In skeletal muscle, these circulating FFAs promote intramyocellular lipid accumulation, disrupting insulin-stimulated glucose uptake through ceramide-mediated inhibition of Akt phosphorylation (376, 377)

Keyword combinations included viral pneumonia, Traditional Chinese Medicine, natural products, inflammation, and oxidative stress, in addition to mechanism-related terms such as NF-B, Nrf2, PI3K/Akt, MAPK, and NLRP3 inflammasome. Natural compounds acting on these pathways have been shown to suppress cytokine storms, reduce reactive oxygen species accumulation, preserve alveolar epithelial integrity, and alleviate pulmonary inflammation