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The role of probiotics and prebiotics in the prevention and treatment of obesity

Diabetes Care 22 (2), B109B113

The direct protective effect of the CYP subunit and its EET metabolites was evidenced by the significant amelioration of cardiac remodeling and heart dysfunction by cardiomyocyte-specific expression of CYP2J2 or treatment with EETs, which decreased the oxidative stressmediated NF-B pathway and PPAR- activation