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Characteristic gross presentation of the lesions, redness, and congestion in the tongue ( upper ), proximal esophagus ( middle ) and duodenum ( lower ) in rats treated with BPC 157 ( B right ) and corresponding controls ( C left )

112,113 Amyotrophic lateral sclerosis Amyotrophic lateral sclerosis (ALS) is a progressive disease characterized by the selective degeneration of motor neurons leading to muscular weakness, muscle atrophy, and eventually death

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K.GretherJ.HansenR.et al

Beyond intracellular sensing via NODs, PGN-derived fragments function as potent signals that trigger the assembly of the NOD-like receptor protein 3 (NLRP3) inflammasome, leading to the maturation and secretion of IL-1