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The authors declare that the funders had no role in the study design, interpretation of the data, the writing of this article or the decision to submit it for publication

At the same time, when POMC and AgRP neurons become resistant to insulin as a consequence of a high-fat diet, neurons expressing SF-1 within the ventromedial nucleus show increased sensitivity, which, in turn, translates into impaired glutamatergic innervation of POMC [49]