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Results are immediate and typically last for several months

For improving memory in people who use alcohol excessively : 2 grams of acetyl-L-carnitine has been used daily for 90 days

Srikantha and Mohajeri, 2019)

Nutrients 11(10):2412

We found that colistin leads to a rapid permeability transition of mitochondria isolated from mouse kidney that was fully prevented by co-incubation of the mitochondria with desensitizers of the mitochondrial transition pore cyclosporin A or L-carnitine