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Some idea of the technique's power is summarised in a synopsis published by Jerne's group in 1965

doi: 10.1039/C5RA20364C 237 ZhouX.CaoQ.OrfilaC.ZhaoJ.ZhangL

Furthermore, a recent meta-analysis documented alterations in superior frontal, lingual gyrus, hippocampus, insula, putamen, superior temporal, inferior temporal gyrus, and anterior cerebellum in the brains of patients with major depression who had a history of ACE [69]