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www.labcorp.com Accessed 6/25/2015

doi: 10.1038/349431a0 33 DukanSFarewellABallesterosMTaddeiFRadmanMNystrmT

GALC dysfunction results in elevated levels of cytotoxic D -galactosylsphingosine in neural tissues, which leads to extensive degeneration of oligodendrocytes and Schwann cells, followed by destructive demyelination