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Fontinha, D

[DOI] [PMC free article] [PubMed] 83.Xiao L, Wu J, Wang JY, Chung HK, Kalakonda S, Rao JN, et al

Upon entering the body, TLK199 undergoes esterase hydrolysis, which releases TLK117, its activated form that has anti-GST activity

l'ester d'thyle d'acide 4-[[[[6-[[(2,4,6-trimthylphnyl)amino]carbonyl]-2-benzothiazolyl]amino] carbonyl]amino]benzoque

Notably, the peptide appeared to alleviate oxidative stress in the neurons and preserved the activity of PP2A, an enzyme involved in dephosphorylating tau proteins