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Mercury exposure in Indian environment due to coal fired thermal power plants and existing legislations

The mechanistic basis involves GHK-CuCuSOD1 (cytoplasmic Cu/Zn-SOD) enhanced activity (NBT reduction assay: +31 5%), reducing HO-driven JNK activation via ASK1-Thr845 phosphorylation (ThioredoxinReductase-Trx1 redox buffer maintained)

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The weight loss was -12.2kg, -13.0kg or -4.8kg, respectively (81)

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As naturally derived nanovesicles with lower immunogenicity, exosomes inherently traverse the BBB, making them an ideal platform for CNS interventions