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SCID mice are reconstituted with human lymphatic cells, e.g., B and/or T cells

The enzyme activities of COXs were determined spectrophotometrically by monitoring the oxidation of N,N,N,N -tetramethyl- p -phenylenediamine (TMPD) at 610 nm during the conversion of PGG 2 to PGH 2

doi: 10.17843/rpmesp.2015.324.1754 26 KwongPDMcDonaldNQSiglerPBHendricksonWA

This synergy enhances dendritic cell maturation and T-cell infiltration, and suppresses Tregs and TAMs, resulting in robust tumor regression and metastasis control with minimal off-target effects

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