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Conclusions We selected a drug model (molecule 356) for its high affinity to isoform A over isoform B of the MAO enzyme

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Holzer M, Birner-Gruenberger R, Stojakovic T, El-Gamal D, Binder V, Wadsack C, Heinemann A, Marsche G

In addition, the chronic expression of the vector protein S gene, in individuals carrying certain HLA haplotypes, could induce immune hyperactivation and excessive production of proinflammatory cytokines, leading to autoimmune hypophysitis or inhibition of ACTH secretion (functional hypopituitarism) (62)

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