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Moreover, patients with ESKD show an expansion of proteolytic bacteria involved in uremic toxins metabolism but a reduced relative abundance of carbohydrate-fermenting bacteria such as Lactobacillacea e and Prevotellaceae families (Wong et al., 2014)

Tomaiuolo, R

The main NRF2-activating drug candidates that have been explored, and many of which have reached different stages of clinical trials, are presented in Table 1