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While IGF-1 has important physiological functions, elevated levels carry potential concerns including increased cell proliferation that may support tumor growth in individuals with cancer or pre-cancerous conditions, accelerated aging processes through growth pathway activation, potential cardiovascular effects with chronic elevation, and metabolic consequences including effects on glucose and lipid metabolism

[PubMed: 19117545] 20

prednisone: 1 patient) but those with severe COVID-19 most often received combinations of two or three drugs of this category, namely dexamethasone, hydrocortisone, and beclomethasone for an average of 11 days before their blood samples were collected

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Its also becoming a common dietary supplement