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doi:10.3109/03602532.2011.558093

(2007) Clin Pract Epidemiol Ment Health, 3: 29

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And finally, the most interesting piece: All of these carnosol effects were nearly similar to those observed with fluoxetine

These pharmacokinetic characteristics reflect ACs poor gastrointestinal absorption, high first-pass metabolism, and possible efflux by transporters such as P-gp, which together significantly limit its oral bioavailability and therapeutic translation