2.4 Association between increased glycolysis with clinical response and survival rates in ALs Despite the strong evidence that glycolytic metabolism can promote chemoresistance in primary leukemic cells from non-responders and/or multiresistant cell lines, recent advances in metabolomics platforms have allowed further investigation into tumor metabolism at the systemic level in patients with acute leukemia (Kim et al., 2021), however, only a few studies have focused on the impact of glycolytic alterations on response to chemotherapy treatment, with mixed results
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Ved sygdom, langvarig medicinbrug, kronisk stress eller alderdom falder patientens egen produktion, mens behovet stiger