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They're distinct classes of compounds with different legal statuses, mechanisms of action, and risk profiles

Methylated CpG sites bind to methylated CpG-binding proteins and interact with other proteins to form abnormal chromatin, which inhibits gene expression (Wasserkort et al., 2013)

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Alcohol can also worsen symptoms of depression itself

This piece is written for researchers and careful readers who want an evidence map rather than a sales pitch: what each component actually shows, what the combination does not show, and why the gap between the two is the most important fact about the product