glutathione production process Glutathione synthesis: A two-step pathway.

Kepp, O., Zitvogel, L

Pull downs were analyzed for interactors and enriched peptides using unbiased mass spectrometry (M/S) for data in main Fig

Toxicol Appl Pharmacol 159:175184 Aravindakumar CT, Ceulemans J, De Ley M (1999) Nitric oxide induces Zn 2+ release from metallothionein by destroying zinc-sulphur clusters without concomitant formation of S-nitrosothiol

2010;298:H1038H1047

These findings suggest that IL-6 plays a significant inflammatory role in liver diseases but is not sufficient on its own to prevent fat accumulation

However, in aralar / animals de-amidation of glutamine in neurons may be impaired as will be discussed below, which may prevent glutamine synthesis in astrocytes