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RT-qPCR was performed with GAPDH as the internal control using the QuantStudio 1 instrument (Applied Biosystems, California, USA), and three replicates were performed

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At work, request a material safety data sheet to help identify safe alternatives, thus avoiding contact with material containing cobalt

Free Radic Res 2010

Most methods employ 1,3-cyclohexanediones, especially dimedone, which already contain a carbonyl at the position that becomes C-5 in the final scaffold ( 2.4 Alternative synthetic routes for underexplored HHQ chemotypes 2.4.1 2-Oxo hexahydroquinolines 2.4.1.1 Enamine-mediated synthesis of 2-oxo HHQ derivatives Enamine-mediated strategies have emerged as versatile approaches for constructing HHQs derivatives, leveraging the high nucleophilicity of the enamine -carbon to facilitate acylation and cyclization

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