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The 80mg dose of febuxostat brought more patients to less than 6mg/dL of uric acid than 300mg of allopurinol, the dose of allopurinol most commonly used

& Rothschild, H

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Cells were washed twice in PBS + 1% FBS and resuspended in 200 L of 7-AAD viability dye diluted 1:200 (Invitrogen, #A1310)

Moreover, the participation of the mitochondria in ferroptosis underscores its metabolic nature, as one of the hallmarks of ferroptosis is a specific morphological phenotype characterized by extensive ultrastructural changes of mitochondria (8)

combining metabolites with clinical variables improved the AUC for predicting nosocomial infection from 0.74 to 0.77