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Older human trials used short intravenous courses

The differential outcomes observed in Figure 3 suggest that the anxiolytic efficacy of the treatments hinges on their specific molecular configurations and the mechanisms by which they modulate neurobiological pathways

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When a gene is "upregulated," it becomes more active and produces more of its protein product

Reported effects on texture and firmness derive from upregulated extracellular matrix production, improved barrier protein expression, and increased fibroblast activity