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Blood-alcohol content (BAC) levels are frequently part of news reports about charges of driving under the influence

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Continuous intravenous infusion of anakinra can effectively control severe and life-threatening cytokine storms caused by diseases such as MAS

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It seeks to establish safety and efficacy before moving into human trials

Comment: One commenter, while generally supporting the proposal and the first alternative, expressed concern that in biosimilar markets with few participants, the proposal and first alternative would provide manufacturers a perverse incentive to employ aggressive rebate strategies or otherwise manipulate pricing data in order that competitor products' ASP data be used as the basis for a more favorable payment limit