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aeruginosa receiving NAC (2,400 mg/day, 4 weeks) showed improved serum antioxidants, reduced oxidative stress, and better FEV 1 % than controls (109)

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10.1073/pnas.88.7.2903 [DOI] [PMC free article] [PubMed] [Google Scholar] Perret V, Garcia A, Grosjean H, Ebel JP, Florentz C, Gieg R

Ma X, Ren X, Guo X, Fu C, Wu Q, Tan L, Li H, Zhang W, Chen X, Zhong H, et al

The four-week minimum exists to allow full physiological adaptation before adding more medication

The rule is: use GHK-Cu in the evening and L-ascorbic acid in the morning, or substitute a stabilized ascorbic acid derivative (ascorbyl glucoside, sodium ascorbyl phosphate) that does not donate electrons as freely to copper